종양 미세환경은 종양 내 혈관신생 행태 조절을 통해 종양의 성장에 기여하고 있음이 보고되고 있음. 본 연구실은 이러한 종양 미세환경의 혈관신생 형질결정에 있어 다양한 신호전달 경로들의 기능규명을 위한 연구들을 다양한 유전자변형 동물모델들을 이용하여 진행하고 있음. 특히 종양 혈관신생 조절에 기여하는 종양 미세환경의 주구성원들인 혈관내피세포, 종양 내 섬유아세포, 종양 침윤 골수유래세포들의 혈관신생 형질결정에 있어 mTOR-S6K 신호경로와 Calcineurin-NFAT 신호경로의 기능 및 그 분자기전 규명에 초점을 맞추어 연구를 진행하고 있음.
학력
3/1997 ~ 2/2002. 포항공과대학교 생명과학과, 이학박사 (지도교수: 성영철)
3/1994 ~ 2/1997. 포항공과대학교 생명과학과, 이학석사 (지도교수: 성영철)
3/1990 ~ 2/1994.포항공과대학교 생명과학과, 이학학사 (지도교수: 성영철)
약력/경력
2020 ~ 현재. 성균관대학교 의과대학, 교수
2014 ~2020. 성균관대학교 의과대학, 부교수
2010 ~2014. 성균관대학교 의과대학, 조교수
2009 ~ 2010 Dept. of Cancer Biology, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Postdoctoral Fellow
2006 ~ 2009 Vascular Biology Program, Department of Surgery, Children’s Hospital, Boston, Harvard Medical School, Research fellow
2003 ~ 2005 국립암센터 간담췌암연구과, 박사 후 연구원
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